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Support and cap: Polyoxymethylene, high rigidity crystalline thermoplastic. Stainless steel needles stabilised with Titanium. Sterilisation via ethylene oxide. Microperforation stimulates angiogenesis by releasing endothelial growth factors.; activating auto repair of skin to create new collagen. Permeability is then increased to absorb active ingredients. Tiny needles rapidly puncturing the skin to induce a natural healing response. By stimulating the skin in this manner, the body starts to produce some of